Regioselective access to polycyclic N-heterocycles via homogeneous copper-catalyzed cascade cyclization of allenynes
Abstract Polycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the cyclization of allenynes remains challenging yet highly desirable. Here we show a homogeneous copper-catalyzed hetero Diels−Alder (HDA) reaction of...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-023-00910-9 |