Regioselective access to polycyclic N-heterocycles via homogeneous copper-catalyzed cascade cyclization of allenynes

Abstract Polycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the cyclization of allenynes remains challenging yet highly desirable. Here we show a homogeneous copper-catalyzed hetero Diels−Alder (HDA) reaction of...

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Bibliographic Details
Main Authors: Kua-Fei Wei, Qing Liu, Guang Ma, Xiao-Lei Jiang, Xiu-Hong Zhu, Guang-Xin Ru, Wen-Bo Shen
Format: Article
Language:English
Published: Nature Portfolio 2023-05-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-023-00910-9