Regioselective access to polycyclic N-heterocycles via homogeneous copper-catalyzed cascade cyclization of allenynes
Abstract Polycyclic N-heterocycles are important structural motifs commonly found in bioactive compounds, however, their selective construction via the cyclization of allenynes remains challenging yet highly desirable. Here we show a homogeneous copper-catalyzed hetero Diels−Alder (HDA) reaction of...
Main Authors: | Kua-Fei Wei, Qing Liu, Guang Ma, Xiao-Lei Jiang, Xiu-Hong Zhu, Guang-Xin Ru, Wen-Bo Shen |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-05-01
|
Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-023-00910-9 |
Similar Items
-
Synthesis of Functionalized Azepines via Cu(I)-Catalyzed Tandem Amination/Cyclization Reaction of Fluorinated Allenynes
by: Anna N. Philippova, et al.
Published: (2022-08-01) -
Enantioselective Rhodium-Catalyzed Cycloisomerization of 1,6-Allenynes to access 5/6-Fused Bicycle[4.3.0]nonadienes
by: Xu Deng, et al.
Published: (2019-02-01) -
Divergent synthesis of N-heterocycles via controllable cyclization of azido-diynes catalyzed by copper and gold
by: Wen-Bo Shen, et al.
Published: (2017-11-01) -
Cyclization of (2-Alkenylphenyl)carbonyl compounds to polycyclic arenes catalyzed by copper(II) trifluoromethanesulfonate or trifluoromethanesulfuric acid
by: Tnay, Ya Lin, et al.
Published: (2013) -
Palladium-catalyzed cascade cyclization of ynamides to azabicycles.
by: Greenaway, R, et al.
Published: (2011)