Optimizing structural modeling for a specific protein scaffold: knottins or inhibitor cystine knots

<p>Abstract</p> <p>Background</p> <p>Knottins are small, diverse and stable proteins with important drug design potential. They can be classified in 30 families which cover a wide range of sequences (1621 sequenced), three-dimensional structures (155 solved) and functio...

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Bibliographic Details
Main Authors: Chiche Laurent, Gracy Jérôme
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/11/535