DNA passes through cohesin’s hinge as well as its Smc3–kleisin interface
The ring model proposes that sister chromatid cohesion is mediated by co-entrapment of sister DNAs inside a single tripartite cohesin ring. The model explains how Scc1 cleavage triggers anaphase but has hitherto only been rigorously tested using small circular mini-chromosomes in yeast, where covale...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2022-09-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/80310 |