Bosentan for high-risk outpatients with COVID-19 infection: a randomized, double blind, placebo-controlled trialResearch in context

Summary: Background: The endothelium is supposedly activated and damaged in COVID-19 because of endothelin-1 over-secretion. This study evaluates the effect of bosentan as an endothelin receptor blocker on the progression of disease in high-risk outpatients with COVID-19 infection. Methods: From 15...

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Bibliographic Details
Main Authors: Shaahin Shahbazi, Zahra Vahdat Shariatpanahi, Erfan Shahbazi
Format: Article
Language:English
Published: Elsevier 2023-08-01
Series:EClinicalMedicine
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537023002948