Pleiotrophin Expression and Actions in Pancreatic β-Cells

Pleiotrophin Expression and Actions in Pancreatic β-Cells

Pleiotrophin (PTN) is a heparin-binding cytokine that is widely expressed during early development and increases in maternal circulation during pregnancy.Aged PTN-deficient mice exhibit insulin resistance, suggesting a role in metabolic control. The objectives of this study were to determine if PTN...

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Bibliographic Details
Main Authors: Julio Sevillano, Aileen Liang, Brenda Strutt, Thomas G. Hill, Sandra Szlapinski, Maria Pilar Ramos-Álvarez, David J. Hill
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Endocrinology
Subjects:
pleiotrophin
β-cell
islet of Langerhans
pancreas
RPTP β/ζ
DNA synthesis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.777868/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.777868/full

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