GSDME with a moonlighting function in pancreatic ductal adenocarcinoma: a narrative review

Pancreatic ductal adenocarcinoma (PDAC) originates in the exocrine pancreas and accounts for 95% of pancreatic cancers, with 5-year survival rates of approximately 10%. Multiple factors are involved in PDAC pathogenesis, including internal genetic alterations and external inflammation-related stimul...

Full description

Bibliographic Details
Main Author: Bo Huang
Format: Article
Language:English
Published: Wolters Kluwer Health/LWW 2022-12-01
Series:Journal of Pancreatology
Online Access:http://journals.lww.com/10.1097/JP9.0000000000000104