In Vitro and In Silico Investigation of BCI Anticancer Properties and Its Potential for Chemotherapy-Combined Treatments

Background: DUSP6 phosphatase serves as a negative regulator of MAPK kinases involved in numerous cellular processes. BCI has been identified as a potential allosteric inhibitor with anticancer activity. Our study was designed to test the anticancer properties of BCI in colon cancer cells, to charac...

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Bibliographic Details
Main Authors: Beata Marciniak, Mateusz Kciuk, Somdutt Mujwar, Rajamanikandan Sundaraj, Karol Bukowski, Renata Gruszka
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/18/4442