Signal Transduction Involving the Dmp1 Transcription Factor and its Alteration in Human Cancer

Summary Dmp1 (cyclin D-interacting myb-like protein 1; also called Dmtf1) is a transcription factor that has been isolated in a yeast two-hybrid screen through its binding property to cyclin D2. Dmp1 directly binds to and activates the Arf promoter and induces Arf-p53-dependent cell cycle arrest in...

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Bibliographic Details
Main Authors: Takayuki Sugiyama, Donna P. Frazier, Pankaj Taneja, Robert D. Kendig, Rachel L. Morgan, Lauren A. Matise, Sarah J. Lagedrost, Kazushi Inoue
Format: Article
Language:English
Published: SAGE Publishing 2008-01-01
Series:Clinical Medicine Insights: Oncology
Online Access:https://doi.org/10.4137/CMO.S548