Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins

Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins

Staphylococcus aureus (SA) leukocidin ED (LukED) belongs to a family of bicomponent pore forming toxins that play important roles in SA immune evasion and nutrient acquisition. LukED targets specific G protein-coupled chemokine receptors to lyse human erythrocytes (red blood cells) and leukocytes (w...

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Bibliographic Details
Main Authors: Paul Lambey, Omolade Otun, Xiaojing Cong, François Hoh, Luc Brunel, Pascal Verdié, Claire M Grison, Fanny Peysson, Sylvain Jeannot, Thierry Durroux, Cherine Bechara, Sébastien Granier, Cédric Leyrat
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
S. aureus
molecular dynamics
GPCRs
crystallography
chemokine receptors
sulfotyrosine
Online Access:https://elifesciences.org/articles/72555

Internet

https://elifesciences.org/articles/72555

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