Realistic three dimensional fitness landscapes generated by self organizing maps for the analysis of experimental HIV-1 evolution.

Human Immunodeficiency Virus type 1 (HIV-1) because of high mutation rates, large population sizes, and rapid replication, exhibits complex evolutionary strategies. For the analysis of evolutionary processes, the graphical representation of fitness landscapes provides a significant advantage. The ex...

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Bibliographic Details
Main Authors: Ramón Lorenzo-Redondo, Soledad Delgado, Federico Morán, Cecilio Lopez-Galindez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3938428?pdf=render