SrrB, a Pseudo-Receptor Protein, Acts as a Negative Regulator for Lankacidin and Lankamycin Production in Streptomyces rochei

SrrB, a Pseudo-Receptor Protein, Acts as a Negative Regulator for Lankacidin and Lankamycin Production in Streptomyces rochei

Streptomyces rochei 7434AN4, a producer of lankacidin (LC) and lankamycin (LM), carries many regulatory genes including a biosynthesis gene for signaling molecules SRBs (srrX), an SRB receptor gene (srrA), and a SARP (Streptomyces antibiotic regulatory protein) family activator gene (srrY). Our prev...

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Bibliographic Details
Main Authors: Yuya Misaki, Shouji Yamamoto, Toshihiro Suzuki, Miyuki Iwakuni, Hiroaki Sasaki, Yuzuru Takahashi, Kuninobu Inada, Haruyasu Kinashi, Kenji Arakawa
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Microbiology
Subjects:
Streptomyces
regulatory cascade
pseudo-receptor
antibiotic
biosynthesis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.01089/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.01089/full

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