ARF6 regulates neuron differentiation through glucosylceramide synthase.

The small GTPase ADP ribosylation factor 6 (ARF6) mediates endocytosis and has in addition been shown to regulate neuron differentiation. Here we investigated whether ARF6 promotes differentiation of Neuro-2a neuronal cells by modifying the cellular lipid composition. We showed that knockdown of ARF...

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Bibliographic Details
Main Authors: Lu Li, Marcus Ståhlman, Mikael Rutberg, Liliana Håversen, Per Fogelstrand, Linda Andersson, Malin Levin, Jan Borén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3610931?pdf=render