Low molecular weight hyaluronan-pulsed human dendritic cells showed increased migration capacity and induced resistance to tumor chemoattraction.

We have shown that ex vivo pre-conditioning of bone marrow-derived dendritic cells (DC) with low molecular weight hyaluronan (LMW HA) induces antitumor immunity against colorectal carcinoma (CRC) in mice. In the present study we investigated the effects of LMW HA priming on human-tumor-pulsed monocy...

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Bibliographic Details
Main Authors: Manglio Rizzo, Juan Bayo, Flavia Piccioni, Mariana Malvicini, Esteban Fiore, Estanislao Peixoto, Mariana G García, Jorge B Aquino, Ariel Gonzalez Campaña, Gustavo Podestá, Marcelo Terres, Oscar Andriani, Laura Alaniz, Guillermo Mazzolini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4169605?pdf=render