Novel H2S-NO hybrid molecule (ZYZ-803) promoted synergistic effects against heart failure

Therapeutic strategies that increase hydrogen sulfide (H2S) or nitric oxide (NO) are cytoprotective in various models of cardiovascular injury. However, the nature of interaction between H2S and NO in heart failure and the underlying mechanisms for the protective effects remain undefined. The presen...

Full description

Bibliographic Details
Main Authors: Dan Wu, Qingxun Hu, Ying Xiong, Deqiu Zhu, Yicheng Mao, Yi Zhun Zhu
Format: Article
Language:English
Published: Elsevier 2018-05-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231717308248