Combined Effects of Cyclooxygenase-1 and Cyclooxygenase-2 Selective Inhibitors on Ovarian Carcinoma in Vivo

Combined Effects of Cyclooxygenase-1 and Cyclooxygenase-2 Selective Inhibitors on Ovarian Carcinoma in Vivo

The present study was designed to investigate the combined effects of cyclooxygenase (COX)-1 and COX-2 selective inhibitors on human ovarian SKOV-3 carcinoma cells xenograft-bearing mice. The animals were treated with 3 mg/kg SC-560 (a COX-1 selective inhibitor) alone, 25 mg/kg celecoxib (a COX-2 se...

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Bibliographic Details
Main Authors: Jun Zhang, Mei-Lin Liu, Ling-Yun Zhai, Hong-Ru Jiang, Xiao-Li Xu, Jie Wang, Wei Li
Format: Article
Language:English
Published: MDPI AG 2011-01-01
Series:International Journal of Molecular Sciences
Subjects:
ovarian carcinoma
mice
cyclooxygenase selective inhibitor
cell proliferation
apoptosis
Online Access:http://www.mdpi.com/1422-0067/12/1/668/

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http://www.mdpi.com/1422-0067/12/1/668/

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