Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma

Relative expression of KLK5 to LEKTI is associated with aggressiveness of oral squamous cell carcinoma

Background: Oral squamous cell carcinoma (OSCC) remains a challenging cancer to treat despite all the advances of the last 50 years. Kallikrein 5 (KLK5) is among the serine proteases implicated in OSCC development. However, whether the activity of KLK5 promotes carcinogenesis is still controversial....

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Main Authors: Márcia Gaião Alves, Márcio Hideki Kodama, Elaine Zayas Marcelino da Silva, Bruno Belmonte Martinelli Gomes, Rodrigo Alberto Alves da Silva, Gabriel Viliod Vieira, Vani Maria Alves, Carol Kobori da Fonseca, Ana Carolina Santana, Nerry Tatiana Cecílio, Mara Silvia Alexandre Costa, Maria Célia Jamur, Constance Oliver, Thiago Mattar Cunha, Thomas H. Bugge, Paulo Henrique Braz-Silva, Leandro M. Colli, Katiuchia Uzzun Sales
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Translational Oncology
Subjects:
OSCC
Kallikrein 5
LEKTIb
SPINK5
Prognostic marker
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523320304629

Internet

http://www.sciencedirect.com/science/article/pii/S1936523320304629

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