Dupilumab normalizes correlates of lysosomal function in atopic dermatitis

Dupilumab normalizes correlates of lysosomal function in atopic dermatitis

Abstract Background Atopic dermatitis (AD) is characterized by skin barrier dysfunction and immune dysregulation. Autophagy, which is important for the epidermal differentiation, is impaired in AD. The treatment with dupilumab, an interleukin (IL)‐4/IL‐13 receptor blocker, has been shown to reduce s...

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Bibliographic Details
Main Authors: Christina Bürgler, Danielle Dutoit, Susanne Radonjic‐Hoesli, Kathrin Thormann, Mathias Lehmann, Shida Yousefi, Hans‐Uwe Simon, Dagmar Simon
Format: Article
Language:English
Published: Wiley 2024-06-01
Series:JEADV Clinical Practice
Subjects:
atopic dermatitis
autophagy
dupilumab
skin barrier
Online Access:https://doi.org/10.1002/jvc2.307

Internet

https://doi.org/10.1002/jvc2.307

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