Effect of miR-21 in mesenchymal stem cells-derived extracellular vesicles behavior

Effect of miR-21 in mesenchymal stem cells-derived extracellular vesicles behavior

Abstract Background A challenging new branch of research related to aging-associated diseases is the identification of miRNAs capable of modulating the senescence-associated secretory phenotype (SASP) which characterizes senescent cells and contributes to driving inflammation. Methods Mesenchymal st...

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Bibliographic Details
Main Authors: Miriam Morente-López, Rocio Mato-Basalo, Sergio Lucio-Gallego, Concha Gil, Mónica Carrera, Juan A. Fafián-Labora, Jesús Mateos, María C. Arufe
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Stem Cell Research & Therapy
Subjects:
Mesenchymal stem cells (MSC)
Extracellular vesicles (EV)
miR-21-5p (miR-21)
Syndecan-1 (SDC1)
Senescence-associated secretory phenotype (SASP)
Inflammaging
Online Access:https://doi.org/10.1186/s13287-023-03613-z

Internet

https://doi.org/10.1186/s13287-023-03613-z

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