New Triazinoindole Bearing Benzimidazole/Benzoxazole Hybrids Analogs as Potent Inhibitors of Urease: Synthesis, In Vitro Analysis and Molecular Docking Studies

New Triazinoindole Bearing Benzimidazole/Benzoxazole Hybrids Analogs as Potent Inhibitors of Urease: Synthesis, In Vitro Analysis and Molecular Docking Studies

Twenty-four analogs based on triazinoindole bearing benzimidazole/benzoxazole moieties (<b>1</b>–<b>25</b>) were synthesized. Utilizing a variety of spectroscopic methods, including <sup>1</sup>H-, <sup>13</sup>C-NMR, and HREI-MS, the newly afforded co...

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Bibliographic Details
Main Authors: Sundas Mumtaz, Shahid Iqbal, Mazloom Shah, Rafaqat Hussain, Fazal Rahim, Wajid Rehman, Shoaib Khan, Obaid-ur-Rahman Abid, Liaqat Rasheed, Ayed A. Dera, Hanan A. Al-ghulikah, Sana Kehili, Eslam B. Elkaeed, Hamad Alrbyawi, Mohammed Issa Alahmdi
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Molecules
Subjects:
synthesis
triazinoindole
benzimidazole
benzoxazole
urease
structure-activity relationship and molecular docking
Online Access:https://www.mdpi.com/1420-3049/27/19/6580

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https://www.mdpi.com/1420-3049/27/19/6580

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