Tumor Suppression by Anti-Fibroblast Activation Protein Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts

Tumor Suppression by Anti-Fibroblast Activation Protein Near-Infrared Photoimmunotherapy Targeting Cancer-Associated Fibroblasts

Cancer-associated fibroblasts (CAFs) constitute a prominent cellular component of the tumor stroma, with various pro-tumorigenic roles. Numerous attempts to target fibroblast activation protein (FAP), a highly expressed marker in immunosuppressive CAFs, have failed to demonstrate anti-tumor efficacy...

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Bibliographic Details
Main Authors: Raisa A. Glabman, Colleen P. Olkowski, Hannah A. Minor, Laura L. Bassel, Noemi Kedei, Peter L. Choyke, Noriko Sato
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
fibroblast activation protein
cancer-associated fibroblast
near-infrared photoimmunotherapy
tumor microenvironment
cancer therapy
Online Access:https://www.mdpi.com/2072-6694/16/2/449

Internet

https://www.mdpi.com/2072-6694/16/2/449

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