Effect of high mobility group box 1 on Toll-like receptor 9 in B cells in myeloperoxidase-ANCA-associated vasculitis

High mobility group box 1 (HMGB1) played pathogenic role in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Recent findings demonstrated that Toll-like receptor 9 (TLR9) was involved in B cell tolerance breaking of autoimmune disease, including AAV. Here, we investigated the...

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Bibliographic Details
Main Authors: Chen Wang, Hui Deng, Yan Gong, Ran You, Min Chen, Ming-Hui Zhao
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Autoimmunity
Subjects:
Online Access:http://dx.doi.org/10.1080/08916934.2019.1696777