Saos‐2 cells cultured under hypoxia rapidly differentiate to an osteocyte‐like stage and support intracellular infection by Staphylococcus aureus

Abstract The intracellular infection of osteocytes represents a clinically important aspect of osteomyelitis. However, few human osteocyte in vitro models exist and the differentiation of immature osteoblasts to an osteocyte stage typically takes at least 4‐weeks of culture, making the study of this...

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Bibliographic Details
Main Authors: Anja R. Zelmer, Yolandi Starczak, Lucian B. Solomon, Katharina Richter, Dongqing Yang, Gerald J. Atkins
Format: Article
Language:English
Published: Wiley 2023-11-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.15851