Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor

<p>Abstract</p> <p>Background</p> <p>Farnesyltransferase inhibitors (FTI) are small molecule agents originally formulated to inhibit the oncogenic functions of Ras. Although subsequent analysis of FTI activity revealed wider effects on other pathways, the drug has been...

Full description

Bibliographic Details
Main Authors: Rothstein Jay L, Testa James S, DeGeorge Brent R, DeGeorge Katharine C
Format: Article
Language:English
Published: BMC 2008-02-01
Series:Journal of Inflammation
Online Access:http://www.journal-inflammation.com/content/5/1/3