Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor
<p>Abstract</p> <p>Background</p> <p>Farnesyltransferase inhibitors (FTI) are small molecule agents originally formulated to inhibit the oncogenic functions of Ras. Although subsequent analysis of FTI activity revealed wider effects on other pathways, the drug has been...
Main Authors: | Rothstein Jay L, Testa James S, DeGeorge Brent R, DeGeorge Katharine C |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-02-01
|
Series: | Journal of Inflammation |
Online Access: | http://www.journal-inflammation.com/content/5/1/3 |
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