Biodistribution and dosimetry of 177Lu-DOTA-IBA for therapy of bone metastases

Biodistribution and dosimetry of 177Lu-DOTA-IBA for therapy of bone metastases

Abstract Background We designed and synthesized a novel bisphosphonate radiopharmaceutical (68 Ga- or 177Lu-labeled DOTA-ibandronate [68 Ga/177Lu-DOTA-IBA]) for the targeted diagnosis and treatment of bone metastases. The biodistribution and internal dosimetry of a single therapeutic dose of 177Lu-D...

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Bibliographic Details
Main Authors: Hongmei Li, Wenjie Pei, Xiqun Yang, Gengcuo Qu, Qingchu Hua, Lin Liu, Yudi Wang, Tingting Xu, Yue Chen
Format: Article
Language:English
Published: SpringerOpen 2024-03-01
Series:EJNMMI Research
Subjects:
177Lu-DOTA-IBA
Dosimetry
Biodistribution
Bone metastasis
Radionuclide therapy
Online Access:https://doi.org/10.1186/s13550-024-01094-6

Internet

https://doi.org/10.1186/s13550-024-01094-6

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