Comprehensive Analysis of C. glutamicum Anaplerotic Deletion Mutants Under Defined d-Glucose Conditions

Comprehensive Analysis of C. glutamicum Anaplerotic Deletion Mutants Under Defined d-Glucose Conditions

Wild-type C. glutamicum ATCC 13032 is known to possess two enzymes with anaplerotic (C4-directed) carboxylation activity, namely phosphoenolpyruvate carboxylase (PEPCx) and pyruvate carboxylase (PCx). On the other hand, C3-directed decarboxylation can be catalyzed by the three enzymes phosphoenolpyr...

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Bibliographic Details
Main Authors: Jannick Kappelmann, Bianca Klein, Mathias Papenfuß, Julian Lange, Bastian Blombach, Ralf Takors, Wolfgang Wiechert, Tino Polen, Stephan Noack
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Corynebacterium glutamicum
anaplerosis
phosphoenolpyruvate carboxylase
pyruvate carboxylase
phosphoenolpyruvate carboxykinase
oxaloacetate decarboxylase
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.602936/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.602936/full

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