Characterization and Follow-Up of Trypanosoma cruzi Natural Populations Refractory to Etiological Chemotherapy in Oral Chagas Disease Patients

Characterization and Follow-Up of Trypanosoma cruzi Natural Populations Refractory to Etiological Chemotherapy in Oral Chagas Disease Patients

We aimed to characterize the genetic constitution of natural T. cruzi populations involved in an Oral Chagas Disease (OCD) outbreak at a rural school of the community of Chichiriviche de la Costa, Venezuela, which affected patients did not respond to the etiological treatment. Peripheral blood sampl...

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Bibliographic Details
Main Authors: Arturo Muñoz-Calderón, Zoraida Díaz-Bello, Belkisyolé Alarcón de Noya, Oscar O. Noya-González, Alejandro G. Schijman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Trypanosoma cruzi
Oral Chagas disease
trypanocidal chemotherapy
therapeutic failure
genetic diversity
restriction fragment length polymorphism
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.665063/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2021.665063/full

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