PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds

PGC-1β modulates catabolism and fiber atrophy in the fasting-response of specific skeletal muscle beds

Objective: Skeletal muscle is a pivotal organ for the coordination of systemic metabolism, constituting one of the largest storage site for glucose, lipids and amino acids. Tight temporal orchestration of protein breakdown in times of fasting has to be balanced with preservation of muscle mass and f...

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Bibliographic Details
Main Authors: Svenia Schmid, Barbara Heim-Kupr, Joaquín Pérez-Schindler, Shivani Mansingh, Markus Beer, Nitish Mittal, Nikolaus Ehrenfeuchter, Christoph Handschin
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Molecular Metabolism
Subjects:
Skeletal muscle
Fasting
PGC-1β
Myostatin
Atrophy
Ubiquitin proteasome
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822002125

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http://www.sciencedirect.com/science/article/pii/S2212877822002125

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