Gut microbiome signature of Viliuisk encephalomyelitis in Yakuts includes an increase in microbes linked to lean body mass and eating behaviour

Gut microbiome signature of Viliuisk encephalomyelitis in Yakuts includes an increase in microbes linked to lean body mass and eating behaviour

Abstract Background Viliuisk encephalomyelitis (VE) is a rare endemic neurodegenerative disease occurring in the Yakut population of Northeastern Siberia. The main clinical features of VE are spasticity, dysarthria, dementia, central paresis and paralysis, and cortical atrophy observed via MRI. Many...

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Bibliographic Details
Main Authors: Veronika Kuznetsova, Alexander Tyakht, Lyudmila Akhmadishina, Vera Odintsova, Natalia Klimenko, Elena Kostryukova, Maria Vakhitova, Tatyana Grigoryeva, Sergey Malanin, Vsevolod Vladimirtsev, Raisa Nikitina, Viktor Volok, Vladimir Osakovskiy, Tatiana Sivtseva, Fyodor Platonov, Dmitry Alexeev, Galina Karganova
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Gut microbiome
Viliuisk encephalomyelitis
Yakuts
16S rRNA sequencing
Methanobrevibacter
Microbiome-gut-brain axis
Online Access:http://link.springer.com/article/10.1186/s13023-020-01612-4

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http://link.springer.com/article/10.1186/s13023-020-01612-4

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