A Computational Approach to Identify the Mutations in the Genes of the RTK Signaling Pathway and their Possible Association with Oral Squamous Cell Carcinoma

A Computational Approach to Identify the Mutations in the Genes of the RTK Signaling Pathway and their Possible Association with Oral Squamous Cell Carcinoma

Background: We aimed to determine the role of receptor tyrosine kinases (RTK) signaling family genes in the development of oral squamous cell carcinoma (OSCC). Method: In the present in silico study, 40 whole genome sequences of patients with OSCC from the cBioPortal was analysed to identify the mut...

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Bibliographic Details
Main Authors: Aditya Jain, Smiline Girija Aseervatham Selvi, Paramasivam Arumugam, Vijayashree Priyadharsini Jayaseelan
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2021-01-01
Series:Middle East Journal of Cancer
Subjects:
oral squamous cell carcinoma
receptor tyrosine kinases
cbioportal
mutations
Online Access:https://mejc.sums.ac.ir/article_46808_103f060939526ae0289762995f0a4f53.pdf

Internet

https://mejc.sums.ac.ir/article_46808_103f060939526ae0289762995f0a4f53.pdf

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