Pathomechanisms of Paclitaxel-Induced Peripheral Neuropathy

Peripheral neuropathy is one of the most common side effects of chemotherapy, affecting up to 60% of all cancer patients receiving chemotherapy. Moreover, paclitaxel induces neuropathy in up to 97% of all gynecological and urological cancer patients. In cancer cells, paclitaxel induces cell death vi...

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Bibliographic Details
Main Authors: Ines Klein, Helmar C. Lehmann
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxics
Subjects:
Online Access:https://www.mdpi.com/2305-6304/9/10/229