Fibin regulates cardiomyocyte hypertrophy and causes protein-aggregate-associated cardiomyopathy in vivo

Fibin regulates cardiomyocyte hypertrophy and causes protein-aggregate-associated cardiomyopathy in vivo

Despite the identification of numerous molecular pathways modulating cardiac hypertrophy its pathogenesis is not completely understood. In this study we define an unexpected role for Fibin (“fin bud initiation factor homolog”) in cardiomyocyte hypertrophy. Via gene expression profiling in hypertroph...

Full description

Bibliographic Details
Main Authors: Matthias Petersen, Nesrin Schmiedel, Franziska Dierck, Susanne Hille, Anca Remes, Frauke Senger, Inga Schmidt, Renate Lüllmann-Rauch, Oliver J. Müller, Derk Frank, Ashraf Y. Rangrez, Norbert Frey, Christian Kuhn
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Molecular Biosciences
Subjects:
fibin
cardiac z-disc
cardiac hypertrophy
SRF signalling
NFAT signalling
protein aggregate associated cardiomyopathy
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1169658/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1169658/full

Similar Items