Antibody-dependent cellular cytotoxicity responses and susceptibility influence HIV-1 mother-to-child transmission
HIV-1 vaccine efforts are primarily directed toward eliciting neutralizing antibodies (nAbs). However, vaccine trials and mother-to-child natural history cohort investigations indicate that antibody-dependent cellular cytotoxicity (ADCC), not nAbs, correlate with prevention. The ADCC characteristics...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
American Society for Clinical investigation
2022-05-01
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Series: | JCI Insight |
Subjects: | |
Online Access: | https://doi.org/10.1172/jci.insight.159435 |