Beyond KRAS: Practical Molecular Targets in Pancreatic Adenocarcinoma

Pancreatic adenocarcinoma (PDAC) has a grim prognosis. Molecular and genomic analyses revealed that the striking majority of these tumors are driven by KRAS mutation, currently not amenable to targeted therapy. However, other driver mutations were found in a small fraction of patients. Herein we rep...

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Bibliographic Details
Main Authors: Albert Grinshpun, Yonaton Zarbiv, Jason Roszik, Vivek Subbiah, Ayala Hubert
Format: Article
Language:English
Published: Karger Publishers 2019-01-01
Series:Case Reports in Oncology
Subjects:
Online Access:https://www.karger.com/Article/FullText/496018