Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2

Cannabis suppresses antitumor immunity by inhibiting JAK/STAT signaling in T cells through CNR2

Abstract The combination of immune checkpoint blockade (ICB) with chemotherapy significantly improves clinical benefit of cancer treatment. Since chemotherapy is often associated with adverse events, concomitant treatment with drugs managing side effects of chemotherapy is frequently used in the com...

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Bibliographic Details
Main Authors: Xinxin Xiong, Siyu Chen, Jianfei Shen, Hua You, Han Yang, Chao Yan, Ziqian Fang, Jianeng Zhang, Xiuyu Cai, Xingjun Dong, Tiebang Kang, Wende Li, Penghui Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2022-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-022-00918-y

Internet

https://doi.org/10.1038/s41392-022-00918-y

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