Pramipexole Upregulates Dopamine Receptor D2 and D3 Expression in Rat Striatum

Randomized clinical trials have shown that pramipexole has an antidepressant effect in patients with Parkinson’s disease. We investigated the comparative efficacy of pramipexole toward dopamine receptor D2 and D3 expression in rat brain. Groups of rats were treated subacutely with pramipexole (1 mg/...

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Bibliographic Details
Main Authors: Naohito Tokunaga, Mohammed Emamussalehin Choudhury, Noriko Nishikawa, Masahiro Nagai, Tomoaki Tujii, Hirotaka Iwaki, Mika Kaneta, Masahiro Nomoto
Format: Article
Language:English
Published: Elsevier 2012-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319304529