High-fat diet combined with dextran sulfate sodium failed to induce a more serious NASH phenotype than high-fat diet alone

High-fat diet combined with dextran sulfate sodium failed to induce a more serious NASH phenotype than high-fat diet alone

Background and Aims: Animal models are essential tools to investigate the pathogenesis of diseases. Disruption in the intestinal epithelial barrier and gut vascular barrier is an early event in the development of non-alcoholic fatty liver disease (NAFLD). Intestinal epithelial barrier can be destroy...

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Bibliographic Details
Main Authors: Yan Zhou, Ya Feng, Lili Yang, Peiyong Zheng, Lu Hang, Fengru Jiang, Jianye Yuan, Lixin Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Pharmacology
Subjects:
non-alcoholic steatohepatitis
animal models
high-fat diet
dextran sulfate sodium
liver fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1022172/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.1022172/full

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