Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection

Combined CD8+ and CD4+ adenovirus hexon-specific T cells associated with viral clearance after stem cell transplantation as treatment for adenovirus infection

Background Human adenovirus can cause morbidity and mortality in immunocompromised patients after allogeneic stem cell transplantation. Reconstitution of adenovirus-specific CD4+ T cells has been reported to be associated with sustained protection from adenovirus disease, but epitope specificity of...

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Main Authors: Maarten L. Zandvliet, J.H. Frederik Falkenburg, Ellis van Liempt, Louise A. Veltrop-Duits, Arjan C. Lankester, Jayant S. Kalpoe, Michel G.D. Kester, Dirk M. van der Steen, Maarten J. van Tol, Roel Willemze, Henk-Jan Guchelaar, Marco W. Schilham, Pauline Meij
Format: Article
Language:English
Published: Ferrata Storti Foundation 2010-11-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/5792

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https://haematologica.org/article/view/5792

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