HLA-C and KIR permutations influence chronic obstructive pulmonary disease risk

HLA-C and KIR permutations influence chronic obstructive pulmonary disease risk

A role for hereditary influences in the susceptibility for chronic obstructive pulmonary disease (COPD) is widely recognized. Cytotoxic lymphocytes are implicated in COPD pathogenesis, and functions of these leukocytes are modulated by interactions between their killer cell Ig-like receptors (KIR) a...

Full description

Bibliographic Details
Main Authors: Takudzwa Mkorombindo, Thi K. Tran-Nguyen, Kaiyu Yuan, Yingze Zhang, Jianmin Xue, Gerard J. Criner, Young-il Kim, Joseph M. Pilewski, Amit Gaggar, Michael H. Cho, Frank C. Sciurba, Steven R. Duncan
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-10-01
Series:JCI Insight
Subjects:
Immunology
Pulmonology
Online Access:https://doi.org/10.1172/jci.insight.150187

Internet

https://doi.org/10.1172/jci.insight.150187

Similar Items