Proton- compared to X-irradiation leads to more acinar atrophy and greater hyposalivation accompanied by a differential cytokine response

Proton- compared to X-irradiation leads to more acinar atrophy and greater hyposalivation accompanied by a differential cytokine response

Abstract Proton therapy gives less dose to healthy tissue compared to conventional X-ray therapy, but systematic comparisons of normal tissue responses are lacking. The aim of this study was to investigate late tissue responses in the salivary glands following proton- or X-irradiation of the head an...

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Bibliographic Details
Main Authors: Inga Solgård Juvkam, Olga Zlygosteva, Mateusz Sitarz, Brita Singers Sørensen, Hans Christian D. Aass, Nina Jeppesen Edin, Hilde Kanli Galtung, Tine Merete Søland, Eirik Malinen
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Series:Scientific Reports
Subjects:
Protons
X-rays
Fractionated irradiation
Mice
Salivary glands
Cytokines
Online Access:https://doi.org/10.1038/s41598-024-73110-7

Internet

https://doi.org/10.1038/s41598-024-73110-7

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