The EIF4A3/CASC2/RORA Feedback Loop Regulates the Aggressive Phenotype in Glioblastomas

Glioblastoma (GBM) is a common and refractory subtype of high-grade glioma with a poor prognosis. The epithelial-mesenchymal transition (EMT) is an important cause of enhanced glioblastoma invasiveness and tumor recurrence. Our previous study found that retinoic acid receptor-related orphan receptor...

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Библиографические подробности
Главные авторы: Junshuang Zhao, Yang Jiang, Lian Chen, Yue Ma, Haiying Zhang, Jinpeng Zhou, Hao Li, Zhitao Jing
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2021-08-01
Серии:Frontiers in Oncology
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Online-ссылка:https://www.frontiersin.org/articles/10.3389/fonc.2021.699933/full