Enhancer and super-enhancer dynamics in repair after ischemic acute kidney injury

Acute kidney injury is a major health problem amongst hospitalized patients. Here the authors provide a comprehensive characterization of enhancer and super-enhancer elements, and the transcription factor motifs associated with these elements in response to kidney injury in vivo; providing insight i...

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Bibliographic Details
Main Authors: Julia Wilflingseder, Michaela Willi, Hye Kyung Lee, Hannes Olauson, Jakub Jankowski, Takaharu Ichimura, Reinhold Erben, M. Todd Valerius, Lothar Hennighausen, Joseph V. Bonventre
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17205-5