Valine-mediated borane reduction of ketones
Acetophenone, 3,3-dimethyl-2-butanone, 3-methyl-2-butanone, and 2-pentanone were reduced with (S)-valine-mediated borane in very good yields (86-91 %) giving predominantly alcohols of the (R)-configuration (80, 64, 55 and 36 % ee, respectively).
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Serbian Chemical Society
2000-08-01
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Series: | Journal of the Serbian Chemical Society |
Subjects: | |
Online Access: | http://www.shd.org.yu/HtDocs/SHD/Vol65/No8-Pdf/jscs8-02.pdf |