Organ dysfunction among piglets treated with inhaled nitric oxide and intravenous hydrocortisone during prolonged endotoxin infusion.

OBJECTIVE: It has previously been shown that a combination of inhaled nitric oxide (iNO) and intravenous (IV) steroid attenuates endotoxin-induced organ damage in a 6-hour porcine endotoxemia model. We aimed to further explore these effects in a 30-hour model with attention to clinically important v...

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Bibliographic Details
Main Authors: Sofie Paues Göranson, Waldemar Goździk, Piotr Harbut, Stanisław Ryniak, Stanisław Zielinski, Caroline Gillis Haegerstrand, Andrzej Kübler, Göran Hedenstierna, Claes Frostell, Johanna Albert
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4020811?pdf=render