Regulatory Evolution Drives Evasion of Host Inflammasomes by Salmonella Typhimurium

Regulatory Evolution Drives Evasion of Host Inflammasomes by Salmonella Typhimurium

Summary: Bacterial two-component regulatory systems (TCS) couple the detection of niche-specific cues with adaptive gene expression to optimize fitness. In Salmonella Typhimurium (STM), the SsrA-SsrB TCS regulates virulence genes needed for survival within host cells, yet the impact of this TCS on r...

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Main Authors: Bushra Ilyas, David T. Mulder, Dustin J. Little, Wael Elhenawy, María M. Banda, Deyanira Pérez-Morales, Caressa N. Tsai, N.Y.E. Chau, Víctor H. Bustamante, Brian K. Coombes
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718315389

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http://www.sciencedirect.com/science/article/pii/S2211124718315389

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