Alterations in oligodendrocyte transcriptional networks reveal region-specific vulnerabilities to neurological disease

Summary: Neurological disease is characterized the by dysfunction of specific neuroanatomical regions. To determine whether region-specific vulnerabilities have a transcriptional basis at cell-type-specific resolution, we analyzed gene expression in mouse oligodendrocytes across various brain region...

Full description

Bibliographic Details
Main Authors: Dario Tommasini, Rachel Fox, Kathie J. Ngo, Jason D. Hinman, Brent L. Fogel
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223004352