Identification of Important Polymorphic Sites on MSH2 Gene in Colorectal Cancer Samples Using High Resolution Melting Point Analysis

Abstract Background and Aim: Colorectal cancer (CRC) is the second most common cancer in developed countries.  More than 10% of CRCs are inherited and include HNPCC and FAP ligation syndrome. The MSH2 gene is located on chromosome 2 (p21) and consists of 16 exons. MSH2 is a protein that plays a role...

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Bibliographic Details
Main Authors: M Nemati, AH Angji, S Aryan, A Bahari
Format: Article
Language:fas
Published: Yasuj University Of Medical Sciences 2018-10-01
Series:Armaghane Danesh Bimonthly Journal
Subjects:
Online Access:http://armaghanj.yums.ac.ir/article-1-1919-en.html