Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet
In this study, IDF from Pyrus ussuriensis Maxim pomace (PUIDF) was prepared, and its routine constituents as well as physicochemical properties and structure were analyzed. Moreover, the effect of PUIDF on obesity and gut microbiota (GM) through a high-fat diet (HFD) mouse model was investigated. Th...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Journal of Functional Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464622004248 |
| _version_ | 1811187650948759552 |
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| author | Fei Peng Xin Ren Bin Du Kui Niu Zuoqing Yu Yuedong Yang |
| author_facet | Fei Peng Xin Ren Bin Du Kui Niu Zuoqing Yu Yuedong Yang |
| author_sort | Fei Peng |
| collection | DOAJ |
| description | In this study, IDF from Pyrus ussuriensis Maxim pomace (PUIDF) was prepared, and its routine constituents as well as physicochemical properties and structure were analyzed. Moreover, the effect of PUIDF on obesity and gut microbiota (GM) through a high-fat diet (HFD) mouse model was investigated. The results demonstrated that PUIDF had a loose and porous surface structure and typical cellulose polysaccharide functional groups with good water holding, oil holding and swelling capacity, as well as glucose and cholesterol adsorption performance in vitro. PUIDF could significantly reduce weight gain and lipid and cholesterol levels in HFD-induced obese mice. More importantly, PUIDF intervention greatly improved the diversity of GM in mice, as well as regulated intestinal microbiota composition and increasing the abundance of short-chain fatty acid producing bacteria. These results suggest that PUIDF may have a positive effect to alleviate hyperlipidemia and improve intestinal bacterial ecosystems. |
| first_indexed | 2024-04-11T14:05:51Z |
| format | Article |
| id | doaj.art-6a8a1ae787284af08ce7ba0dc206f520 |
| institution | Directory Open Access Journal |
| issn | 1756-4646 |
| language | English |
| last_indexed | 2024-04-11T14:05:51Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Functional Foods |
| spelling | doaj.art-6a8a1ae787284af08ce7ba0dc206f5202022-12-22T04:19:53ZengElsevierJournal of Functional Foods1756-46462022-12-0199105354Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat dietFei Peng0Xin Ren1Bin Du2Kui Niu3Zuoqing Yu4Yuedong Yang5Hebei Key Laboratory of Active Components and Functions in Natural Products, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China; Engineering Research Center of Chestnut Industry Technology, Ministry of Education, Hebei Normal University of Science and Technology, Qinhuangdao 066000, ChinaHebei Key Laboratory of Active Components and Functions in Natural Products, Hebei Normal University of Science and Technology, Qinhuangdao 066000, ChinaHebei Key Laboratory of Active Components and Functions in Natural Products, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China; Engineering Research Center of Chestnut Industry Technology, Ministry of Education, Hebei Normal University of Science and Technology, Qinhuangdao 066000, ChinaHebei Key Laboratory of Active Components and Functions in Natural Products, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China; Engineering Research Center of Chestnut Industry Technology, Ministry of Education, Hebei Normal University of Science and Technology, Qinhuangdao 066000, ChinaHebei Key Laboratory of Active Components and Functions in Natural Products, Hebei Normal University of Science and Technology, Qinhuangdao 066000, ChinaHebei Key Laboratory of Active Components and Functions in Natural Products, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China; Engineering Research Center of Chestnut Industry Technology, Ministry of Education, Hebei Normal University of Science and Technology, Qinhuangdao 066000, China; Corresponding author at: Hebei Normal University of Science and Technology, No. 360 Hebei Road, Haigang District, Qinhuangdao 066000, China.In this study, IDF from Pyrus ussuriensis Maxim pomace (PUIDF) was prepared, and its routine constituents as well as physicochemical properties and structure were analyzed. Moreover, the effect of PUIDF on obesity and gut microbiota (GM) through a high-fat diet (HFD) mouse model was investigated. The results demonstrated that PUIDF had a loose and porous surface structure and typical cellulose polysaccharide functional groups with good water holding, oil holding and swelling capacity, as well as glucose and cholesterol adsorption performance in vitro. PUIDF could significantly reduce weight gain and lipid and cholesterol levels in HFD-induced obese mice. More importantly, PUIDF intervention greatly improved the diversity of GM in mice, as well as regulated intestinal microbiota composition and increasing the abundance of short-chain fatty acid producing bacteria. These results suggest that PUIDF may have a positive effect to alleviate hyperlipidemia and improve intestinal bacterial ecosystems.http://www.sciencedirect.com/science/article/pii/S1756464622004248Pyrus ussuriensis MaximInsoluble dietary fiberObesityHyperlipidemiaGut microbiota |
| spellingShingle | Fei Peng Xin Ren Bin Du Kui Niu Zuoqing Yu Yuedong Yang Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet Journal of Functional Foods Pyrus ussuriensis Maxim Insoluble dietary fiber Obesity Hyperlipidemia Gut microbiota |
| title | Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet |
| title_full | Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet |
| title_fullStr | Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet |
| title_full_unstemmed | Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet |
| title_short | Insoluble dietary fiber of pear fruit pomace (Pyrus ussuriensis Maxim) consumption ameliorates alterations of the obesity-related features and gut microbiota caused by high-fat diet |
| title_sort | insoluble dietary fiber of pear fruit pomace pyrus ussuriensis maxim consumption ameliorates alterations of the obesity related features and gut microbiota caused by high fat diet |
| topic | Pyrus ussuriensis Maxim Insoluble dietary fiber Obesity Hyperlipidemia Gut microbiota |
| url | http://www.sciencedirect.com/science/article/pii/S1756464622004248 |
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