Compensatory cross-talk between autophagy and glycolysis regulates senescence and stemness in heterogeneous glioblastoma tumor subpopulations

Abstract Despite tremendous research efforts, successful targeting of aberrant tumor metabolism in clinical practice has remained elusive. Tumor heterogeneity and plasticity may play a role in the clinical failure of metabolism-targeting interventions for treating cancer patients. Moreover, compensa...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Emma Martell, Helgi Kuzmychova, Harshal Senthil, Esha Kaul, Chirayu R. Chokshi, Chitra Venugopal, Christopher M. Anderson, Sheila K. Singh, Tanveer Sharif
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2023-07-01
Σειρά:Acta Neuropathologica Communications
Θέματα:
Διαθέσιμο Online:https://doi.org/10.1186/s40478-023-01604-y